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1. (WO2019004610) COMPOSITION FOR PREVENTING OR TREATING HEARING LOSS, CONTAINING VITIS VINIFERA LEAF EXTRACT AS ACTIVE INGREDIENT
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Pub. No.: WO/2019/004610 International Application No.: PCT/KR2018/006144
Publication Date: 03.01.2019 International Filing Date: 30.05.2018
IPC:
A61K 36/87 (2006.01) ,A61K 36/258 (2006.01) ,A61K 36/16 (2006.01) ,A61K 31/05 (2006.01) ,A23L 33/105 (2016.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
87
Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
25
Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
258
Panax (ginseng)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
16
Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
045
Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
05
Phenols
[IPC code unknown for A23L 33/105]
Applicants:
아주대학교산학협력단 AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION [KR/KR]; 경기도 수원시 영통구 월드컵로 206 206, World cup-ro, Yeongtong-gu Suwon-si Gyeonggi-do 16499, KR
Inventors:
정연훈 CHOUNG, Yun-Hoon; KR
김영선 LEE, Young Sun; KR
박영준 PARK, Young-Joon; KR
Agent:
이처영 LEE, Cheo Young; KR
장제환 CHANG, Je Hwan; KR
Priority Data:
10-2017-008182728.06.2017KR
Title (EN) COMPOSITION FOR PREVENTING OR TREATING HEARING LOSS, CONTAINING VITIS VINIFERA LEAF EXTRACT AS ACTIVE INGREDIENT
(FR) COMPOSITION POUR PRÉVENIR OU TRAITER LA PERTE AUDITIVE, CONTENANT UN EXTRAIT DE FEUILLES DE VITIS VINIFERA À TITRE DE PRINCIPE ACTIF
(KO) 적포도잎 추출물을 유효성분으로 함유하는 난청의 예방 또는 치료용 조성물
Abstract:
(EN) The present invention relates to a composition for preventing or treating hearing loss, containing a Vitis vinifera leaf extract as an active ingredient. A pharmaceutical composition for preventing or treating hearing loss, containing the extract (a Vitis vinifera leaf extract) of the present invention as an active ingredient, protects auditory hair cells in the cochlea and spiral ganglion cells from damage caused by noise and the like and effectively reduces the hearing threshold measured in the auditory nerves, thereby being usable as an agent for preventing or treating hearing loss.
(FR) La présente invention concerne une composition pour prévenir ou traiter la perte auditive, contenant un extrait de feuilles de Vitis vinifera à titre de principe actif. La composition pharmaceutique pour prévenir ou traiter la perte auditive, contenant l'extrait (extrait de feuilles de Vitis vinifera) selon la présente invention ) à titre de principe actif, protège les cellules ciliées auditives dans la cochlée et les cellules du ganglion spiral contre les dommages provoqués par le bruit et autres et réduit efficacement le seuil auditif mesuré dans les nerfs auditifs, et peut donc être utilisée à titre d'agent pour prévenir ou traiter une perte auditive.
(KO) 본 발명은 적포도잎 추출물을 유효성분으로 포함하는 난청의 예방 또는 치료용 조성물에 관한 것으로, 본 발명의 추출물(vitis vinifera leaf extract)를 유효성분으로 함유하는 난청 예방 또는 치료용 약학 조성물은 소음 등으로 인한 와우 내 청각 유모세포 및 나선 신경절 세포의 손상을 보호하고, 청신경에서 측정되는 청력역치를 효과적으로 감소시키므로, 난청의 예방 또는 치료제로 유용하게 사용될 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)