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1. (WO2019002536) NOVEL MIRNA BIOMARKERS AND USE THEREOF
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Pub. No.: WO/2019/002536 International Application No.: PCT/EP2018/067547
Publication Date: 03.01.2019 International Filing Date: 29.06.2018
IPC:
C12N 15/113 (2010.01) ,C12Q 1/6876 (2018.01) ,A61K 31/713 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
113
Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
[IPC code unknown for C12Q 1/6876]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7088
Compounds having three or more nucleosides or nucleotides
713
Double-stranded nucleic acids or oligonucleotides
Applicants:
HUMMINGBIRD DIAGNOSTICS GMBH [DE/DE]; Im Neuenheimer Feld 583 69120 Heidelberg, DE
Inventors:
KOHLHAAS, Jochen; DE
KELLER, Andreas; DE
BEIER, Markus; DE
Agent:
GELING, Andrea; DE
Priority Data:
17179051.230.06.2017EP
Title (EN) NOVEL MIRNA BIOMARKERS AND USE THEREOF
(FR) NOUVEAUX BIOMARQUEURS À BASE D'ARNMI ET LEUR UTILISATION
Abstract:
(EN) The present invention relates to novel nucleic acid molecules (novel miRNAs) as well as vectors, host cells, primers, cDNA-transcripts, polynucleotides derived from said nucleic acid molecules and their use in diagnosis, prognosis,and/or therapy. In addition, the present invention relates to methods, means, and kits for diagnosing and/or prognosing a disease for detecting said novel nucleic acid molecules (novel miRNAs molecules).
(FR) La présente invention concerne de nouvelles molécules d'acides nucléiques (nouveaux ARNmi) ainsi que des vecteurs, des cellules hôtes, des amorces, des produits de transcription de l'ADNc, des polynucléotides dérivés desdites molécules d'acides nucléiques et leur utilisation à des fins de diagnostic, de pronostic et de thérapie. De plus, la présente invention concerne des procédés, des moyens et des kits pour diagnostiquer et/ou pronostiquer une maladie afin de détecter lesdites nouvelles molécules d'acide nucléique (nouvelles molécules d'ARNmi).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)