Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019001339) NOVEL TUMOR VACCINE AND USE THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/001339 International Application No.: PCT/CN2018/092198
Publication Date: 03.01.2019 International Filing Date: 21.06.2018
IPC:
A61K 39/00 (2006.01) ,A61K 39/39 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
39
characterised by the immunostimulating additives, e.g. chemical adjuvants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
四川大学 SI CHUAN UNIVERSITY [CN/CN]; 中国四川省成都市 武侯区一环路南一段24号 No.24, South Section 1, First Ring Road, Wuhou District Chengdu, Sichuan 610065, CN
成都金凯生物技术有限公司 GENEKEY BIOTECH (CHENGDU) CO., LTD. [CN/CN]; 中国四川省成都市 高新区科园南路1号海特国际广场4号楼301 No.301, No.4 Buliding, Haite International Plaza, No.1 Keyuan South Road, Hi-Tech Zone Chengdu, Sichuan 610041, CN
深圳信立泰药业股份有限公司 SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD. [CN/CN]; 中国广东省深圳市 福田区深南大道6009号车公庙绿景广场主楼37层 37F, Main Tower, Lvjing Plaza, Che Gong Miao, No. 6009 Shennan Road, Futian District Shenzhen, Guangdong 518040, CN
Inventors:
魏霞蔚 WEI, Xiawei; CN
赵霞 ZHAO, Xia; CN
魏于全 WEI, Yuquan; CN
赵斌 ZHAO, Bin; CN
赵志伟 ZHAO, Zhiwei; CN
彭飞 PENG, Fei; CN
王杨 WANG, Yang; CN
Agent:
成都虹桥专利事务所(普通合伙) CHENGDU HONGQIAO PATENT LAW OFFICE; 中国四川省成都市 高新区天仁路259号1栋3层301-305号、306-1号、318-320号 Room 301-305, 306-1, 318-320, 3rd Floor Building 1, No.259 Tianren Road, Hi-Tech Zone Chengdu, Sichuan 610000, CN
Priority Data:
201710509396.628.06.2017CN
Title (EN) NOVEL TUMOR VACCINE AND USE THEREOF
(FR) NOUVEAU VACCIN ANTITUMORAL ET SON UTILISATION
(ZH) 一种新型的肿瘤疫苗及其用途
Abstract:
(EN) The present invention provides a tumor vaccine with a complex as a main active ingredient, wherein the complex is formed by a nucleic acid, especially a replicable nucleic acid not expressing exogenous genes, and a cationic biomaterial. The nucleic acid and cationic biomaterial in the tumor vaccine of the present invention have synergistic interactions on direct killing of tumor cells, induction of the innate immune response and adaptive immune response of the body against the tumor, etc.
(FR) La présente invention concerne un vaccin antitumoral comprenant un complexe en tant que principe actif principal, le complexe étant formé par un acide nucléique, en particulier un acide nucléique réplicable n’exprimant pas de gènes exogènes, et un biomatériau cationique. L'acide nucléique et le biomatériau cationique dans le vaccin antitumoral de la présente invention ont des interactions synergiques sur la destruction directe de cellules tumorales, l'induction de la réponse immunitaire innée et la réponse immunitaire adaptative du corps contre la tumeur, etc.
(ZH) 本发明提供了一种由核酸,尤其是不表达外源基因的可复制的核酸,与阳离子生物材料形成的复合物为主要活性成分的肿瘤疫苗,本发明肿瘤疫苗中的核酸与阳离子生物材料在直接杀伤肿瘤细胞、诱导机体天然免疫应答和适应性免疫应答抗肿瘤等方面具有协同增效的作用。
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)