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1. (WO2018226880) A HTP GENOMIC ENGINEERING PLATFORM FOR IMPROVING ESCHERICHIA COLI
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Pub. No.: WO/2018/226880 International Application No.: PCT/US2018/036333
Publication Date: 13.12.2018 International Filing Date: 06.06.2018
IPC:
C12N 15/10 (2006.01) ,C12N 15/73 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
10
Processes for the isolation, preparation or purification of DNA or RNA
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
70
Vectors or expression systems specially adapted for E. coli
73
Expression systems using phage lambda regulatory sequences
Applicants:
ZYMERGEN INC. [US/US]; 5980 Horton Street, Suite 105 Emeryville, California 94608, US
Inventors:
SERBER, Zach; US
DEAN, Erik Jedediah; US
MANCHESTER, Shawn; US
GORA, Katherine; US
SHELLMAN, Erin; US
KIMBALL, Aaron; US
SZYJKA, Shawn; US
FREWEN, Barbara; US
TREYNOR, Thomas; US
FLASHMAN, Michael; US
HAUSHALTER, Robert; US
MORGAN, Stacy-Anne; US
BLAISSE, Michael; US
RAMAKRISHNAN, Prabha; US
ROTHSCHILD-MANCINELLI, Kyle; US
KIM, Youngnyun; US
DAVIS, Matthew; US
WISNEWSKI, Christy; US
WESTFALL, Patrick; US
Agent:
HOLLY, David Christopher; US
MCEVOY, Michael T.; US
VEITENHEIMER, Erich E.; US
Priority Data:
62/515,87006.06.2017US
Title (EN) A HTP GENOMIC ENGINEERING PLATFORM FOR IMPROVING ESCHERICHIA COLI
(FR) PLATE-FORME D'INGÉNIERIE GÉNOMIQUE HTP PERMETTANT D'AMÉLIORER ESCHERICHIA COLI
Abstract:
(EN) The present disclosure provides a HTP genomic engineering platform for improving Escherichia coli. that is computationally driven and integrates molecular biology, automation, and advanced machine learning protocols. This integrative platform utilizes a suite of HTP molecular tool sets to create HTP genetic design libraries, which are derived from, inter alia, scientific insight and iterative pattern recognition.
(FR) La présente invention concerne une plateforme d'ingénierie génomique HTP pour améliorer Escherichia coli qui est dirigée par ordinateur et intègre la biologie moléculaire, l'automatisation et des protocoles d'apprentissage machine avancés. Cette plateforme d'intégration utilise une série d'ensembles d'outils moléculaires HTP pour créer des bibliothèques de modèles génétiques HTP qui proviennent, entre autres, de connaissances scientifiques et de reconnaissance de formes itératives.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)