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1. (WO2018226757) SCREENING SYSTEM AND METHODS FOR IDENTIFYING ENZYME SUBSTRATES AND MODULATORS OF ENZYME ACTIVITY
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Pub. No.: WO/2018/226757 International Application No.: PCT/US2018/036148
Publication Date: 13.12.2018 International Filing Date: 05.06.2018
IPC:
C07K 19/00 (2006.01) ,C12N 15/62 (2006.01) ,G01N 21/63 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
19
Hybrid peptides
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
62
DNA sequences coding for fusion proteins
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21
Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible, or ultra-violet light
62
Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63
optically excited
Applicants:
SIVARAMAKRISHNAN, Sivaraj [US/US]; US
SOMMESE, Ruth [US/US]; US
Inventors:
SIVARAMAKRISHNAN, Sivaraj; US
SOMMESE, Ruth; US
Agent:
KAYTOR, Elizabeth N.; US
FINN III, J. Patrick; US
Priority Data:
62/515,20405.06.2017US
Title (EN) SCREENING SYSTEM AND METHODS FOR IDENTIFYING ENZYME SUBSTRATES AND MODULATORS OF ENZYME ACTIVITY
(FR) SYSTÈME DE CRIBLAGE ET MÉTHODES D'IDENTIFICATION DE SUBSTRATS ENZYMATIQUES ET DE MODULATEURS DE L'ACTIVITÉ ENZYMATIQUE
Abstract:
(EN) Materials and methods for identifying modulators of protein function (e.g., enzyme activity), including modulators that target particular substrates for enzymes, are provided herein.
(FR) L'invention concerne des matériels et des méthodes permettant d'identifier des modulateurs de la fonction protéique (par exemple, l'activité enzymatique), notamment des modulateurs ciblant des substrats particuliers pour des enzymes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)