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1. (WO2018226205) METHOD AND SYSTEM FOR SURFACE MODIFICATION OF SUBSTRATE FOR ION BEAM TARGET
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Pub. No.: WO/2018/226205 International Application No.: PCT/US2017/035962
Publication Date: 13.12.2018 International Filing Date: 05.06.2017
IPC:
G21K 1/00 (2006.01) ,G21K 5/04 (2006.01) ,A61N 5/10 (2006.01)
G PHYSICS
21
NUCLEAR PHYSICS; NUCLEAR ENGINEERING
K
TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
1
Arrangements for handling particles or ionising radiation, e.g. focusing or moderating
G PHYSICS
21
NUCLEAR PHYSICS; NUCLEAR ENGINEERING
K
TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
5
Irradiation devices
04
with beam-forming means
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
N
ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5
Radiation therapy
10
X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
Applicants:
PARK, William, H., JR. [US/US]; US
LAMBERT, Mark [US/US]; US
GILLESPIE, Joseph [US/US]; US
SMICK, Noah [US/US]; US
SAKASE, Takao [US/US]; US
NEUTRON THERAPEUTICS, INC. [US/US]; 1 Industrial Drive Danvers, MA 01923, US
Inventors:
PARK, William, H., JR.; US
LAMBERT, Mark; US
GILLESPIE, Joseph; US
SMICK, Noah; US
SAKASE, Takao; US
Agent:
PARK, Larissa, Bifano; US
LANGE, Kristoffer, W.; US
CLARK, Jeffrey, S.; US
GHOSH, Sanjukta; US
GARVEY, John, M.; US
Priority Data:
Title (EN) METHOD AND SYSTEM FOR SURFACE MODIFICATION OF SUBSTRATE FOR ION BEAM TARGET
(FR) PROCÉDÉ ET SYSTÈME DE MODIFICATION DE SURFACE D'UN SUBSTRAT DESTINÉ À UNE CIBLE DE FAISCEAU IONIQUE
Abstract:
(EN) Design and making methods of a neutrons generating target are described. In some embodiments, a surface of a target substrate can be modified to form one or more surface features. In some embodiments, a neutron source layer can be disposed on the surface of the target substrate. In some embodiments, the neutron source layer and the target substrate can be heated to an elevated temperature to form a bond between the two. In some embodiments, the surface modification of the target substrate can reduce blistering and material exfoliation in the target. The target can be used in boron neutron capture therapy.
(FR) L'invention concerne des procédés de conception et de fabrication d'une cible générant des neutrons. Dans certains modes de réalisation, une surface d'un substrat cible peut être modifiée pour former une ou plusieurs caractéristiques de surface. Dans certains modes de réalisation, une couche de source de neutrons peut être disposée sur la surface du substrat cible. Dans certains modes de réalisation, la couche de source de neutrons et le substrat cible peuvent être chauffés à une température élevée pour former une liaison entre les deux. Dans certains modes de réalisation, la modification de surface du substrat cible peut réduire le cloquage et l'exfoliation de matériau dans la cible. La cible peut être utilisée dans une thérapie de capture de neutrons de bore.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)