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1. (WO2018226060) COMPOSITION FOR PREVENTING OR TREATING KIDNEY DISEASE INCLUDING CUDRATRICUSXANTHONE A HAVING KIDNEY-PROTECTING ACTIVITY AS ACTIVE INGREDIENT
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Pub. No.: WO/2018/226060 International Application No.: PCT/KR2018/006508
Publication Date: 13.12.2018 International Filing Date: 08.06.2018
IPC:
A61K 31/352 (2006.01) ,A61K 36/605 (2006.01) ,A23L 33/10 (2016.01) ,A23L 33/105 (2016.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
35
having six-membered rings with one oxygen as the only ring hetero atom
352
condensed with carbocyclic rings, e.g. cannabinols, methantheline
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
60
Moraceae (Mulberry family), e.g. breadfruit or fig
605
Morus (mulberry)
[IPC code unknown for A23L 33/10][IPC code unknown for A23L 33/105]
Applicants:
계명대학교 산학협력단 INDUSTRY ACADEMIC COOPERATION FOUNDATION KEIMYUNG UNIVERSITY [KR/KR]; 대구시 달서구 달구벌대로 1095 1095, Dalgubeol-daero Dalseo-gu Daegu 42601, KR
경북대학교 산학협력단 KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION [KR/KR]; 대구시 북구 대학로 80 (산격동, 경북대학교) (Kyungpook National University, Sangyeok-dong), 80, Daehak-ro Buk-gu Daegu 41566, KR
Inventors:
정길생 JEONG, Gil-Saeng; KR
배종섭 BAE, Jong-Sup; KR
Agent:
특허법인 태백 TAEBAEK INTELLECTUAL PROPERTY LAW FIRM; 서울시 금천구 가산디지털1로151 이노플렉스1차 601호 #601 Innoplex 1 cha, 151Gasandigital 1-ro Geumcheon-gu Seoul 08506, KR
Priority Data:
10-2017-007270809.06.2017KR
Title (EN) COMPOSITION FOR PREVENTING OR TREATING KIDNEY DISEASE INCLUDING CUDRATRICUSXANTHONE A HAVING KIDNEY-PROTECTING ACTIVITY AS ACTIVE INGREDIENT
(FR) COMPOSITION POUR LA PRÉVENTION OU LE TRAITEMENT D'UNE MALADIE RÉNALE CONTENANT DE LA CUDRATRICUSXANTHONE A AYANT UNE ACTIVITÉ DE PROTECTION DES REINS À TITRE DE PRINCIPE ACTIF
(KO) 신장 보호 활성을 갖는 쿠드라트리쿠스잔톤 A를 유효성분으로 포함하는 신장 질환 예방 또는 치료용 조성물
Abstract:
(EN) The present invention relates to a pharmaceutical composition for preventing or treating kidney disease, a health functional food composition, or a health functional food composition for protecting the kidneys, the compositions including cudratricusxanthone A having a kidney-protecting activity as an active ingredient. Cudratricusxanthone A reduces kidney toxicity in a mouse model having damaged kidney function and exhibits an effect of protecting the kidneys from oxidative stress, and thus compositions including cudratricusxanthone A as an active ingredient can be usefully utilized as compositions for preventing, improving, or treating kidney disease, or as functional health food compositions for protecting the kidneys.
(FR) La présente invention concerne une composition pharmaceutique pour prévenir ou traiter une maladie rénale, une composition alimentaire fonctionnelle pour la santé, ou une composition alimentaire fonctionnelle pour la santé visant à protéger les reins, où les compositions contiennent de la cudratricusxanthone A ayant une activité de protection des reins à titre de principe actif. La cudratricusxanthone A réduit la toxicité rénale dans un modèle murin ayant une fonction rénale endommagée et exerce un effet de protection des reins contre le stress oxydatif, et les compositions contenant de la cudratricusxanthone A à titre de principe actif peuvent par conséquent être utilisées de manière utile comme compositions pour prévenir, améliorer ou traiter une maladie rénale, ou comme compositions alimentaires fonctionnelles de santé visant à protéger les reins.
(KO) 본 발명은 신장 보호 활성을 갖는 쿠드라트리쿠스잔톤 A(Cudratricusxanthone A)를 유효성분으로 포함하는 신장 질환 예방 또는 치료용 약학 조성물, 건강기능식품 조성물 또는 신장 보호용 건강기능식품 조성물에 관한 것으로, 상기 쿠드라트리쿠스잔톤 A는 신장 기능이 손상된 마우스 모델에서 신장의 독성을 감소시키고 산화적 스트레스로부터 신장을 보호하는 효과를 나타낸 바, 이를 유효성분으로 포함하는 조성물은 신장 질환 예방, 개선, 치료용 조성물 내지는 신장 보호용 건강기능식품 조성물로 유용하게 활용될 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)