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1. (WO2018225167) AMMONIA METABOLISM PROMOTER
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Pub. No.: WO/2018/225167 International Application No.: PCT/JP2017/021041
Publication Date: 13.12.2018 International Filing Date: 07.06.2017
IPC:
A61K 31/353 (2006.01) ,A61K 31/198 (2006.01) ,A61P 1/16 (2006.01) ,A61P 3/02 (2006.01) ,A61P 25/00 (2006.01) ,A61P 43/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
35
having six-membered rings with one oxygen as the only ring hetero atom
352
condensed with carbocyclic rings, e.g. cannabinols, methantheline
353
3,4-Dihydrobenzopyrans, e.g. chroman, catechin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
195
having an amino group
197
the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid (GABA), beta-alanine, epsilon-aminocaproic acid, pantothenic acid
198
Alpha-amino acids, e.g. alanine, edetic acid (EDTA)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
16
for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
02
Nutrients, e.g. vitamins, minerals
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
Applicants:
花王株式会社 KAO CORPORATION [JP/JP]; 東京都中央区日本橋茅場町一丁目14番10号 14-10, Nihonbashi Kayabacho 1-chome, Chuo-ku, Tokyo 1038210, JP
Inventors:
陳 シュ CHIN, Shu; JP
太田 宣康 OTA, Noriyasu; JP
蓮村 卓広 HASUMURA, Takahiro; JP
Agent:
特許業務法人アルガ特許事務所 THE PATENT CORPORATE BODY ARUGA PATENT OFFICE; 東京都中央区日本橋人形町1丁目3番8号 沢の鶴人形町ビル Sawanotsuru Ningyocho Bldg., 1-3-8, Nihonbashi Ningyocho, Chuo-ku, Tokyo 1030013, JP
Priority Data:
Title (EN) AMMONIA METABOLISM PROMOTER
(FR) PROMOTEUR DE MÉTABOLISME D’AMMONIAC
(JA) アンモニア代謝促進剤
Abstract:
(EN) Provided are a material that promotes ammonia metabolism in the body, and a material that has an excellent ammonia metabolism ameliorative action and is effective for improving stamina and resisting fatigue. Also provided are: an ammonia metabolism promoter comprising a catechin as an active ingredient; a prophylactic or ameliorative agent for hyperammonemia, hepatic encephalopathy, or chronic fatigue syndrome, the prophylactic or ameliorative agent comprising a catechin as an active ingredient; and an ammonia metabolism promoter, a stamina improvement agent, and an anti-fatigue agent comprising a catechin, citrulline, and arginine as active ingredients.
(FR) L’invention fournit une substance qui promeut le métabolisme de l’ammoniac à l’intérieur du corps, et une substance qui présente une excellente action pour l’amélioration du métabolisme de l’ammoniac, et qui se révèle avantageuse en termes d’amélioration de l’endurance et de lutte contre la fatigue. Plus précisément, l’invention concerne un promoteur de métabolisme d’ammoniac ayant des catéchines en tant que principe actif. L’invention concerne également un agent de prévention ou d’amélioration de l’hyperammoniémie, de l’encéphalopathie hépatique ou du syndrome de fatigue chronique, ayant des catéchines en tant que principe actif. Ainsi, l’invention concerne un promoteur de métabolisme d’ammoniac, un agent d’amélioration de l’endurance et un agent de lutte contre la fatigue, ayant des catéchines, une citrulline et une arginine en tant que principes actifs.
(JA) 体内のアンモニア代謝を促進する素材、および優れたアンモニア代謝改善作用を有し、持久力向上および抗疲労に有効な素材の提供。カテキン類を有効成分とするアンモニア代謝促進剤。カテキン類を有効成分とする高アンモニア血症、肝性脳症もしくは慢性疲労症候群の予防もしくは改善剤。カテキン類、シトルリンおよびアルギニンを有効成分とするアンモニア代謝促進剤、持久力向上剤および抗疲労剤。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)