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1. (WO2018223006) PREDICTIVE FACTORS FOR ACUTE KIDNEY INJURY

Pub. No.:    WO/2018/223006    International Application No.:    PCT/US2018/035618
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Sat Jun 02 01:59:59 CEST 2018
IPC: G01N 33/53
G01N 33/00
G01N 33/566
A61K 35/12
A61K 35/22
Applicants: THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.
Inventors: MUNOZ, Beau
SCHOBEL-MCHUGH, Seth A.
ELSTER, Eric A.
GAUCHER, Beverly J.
Title: PREDICTIVE FACTORS FOR ACUTE KIDNEY INJURY
Abstract:
The present invention relates to methods of determining if a subject has an increased risk of developing acute kidney injury (AKI) prior to the onset of any detectable symptoms thereof. The methods comprise analyzing at least one sample from the subject to determine a value of the subject's risk profile and comparing the value of the subject's risk profile with the value of a normal risk profile. A change in the value of the subject's risk profile, over or under normal values is indicative that the subject has an increased risk of having or developing symptoms associated with AKI prior to the onset of any detectable symptoms thereof.