Search International and National Patent Collections

1. (WO2018222991) PEPTIDE PAC1 ANTAGONISTS

Pub. No.:    WO/2018/222991    International Application No.:    PCT/US2018/035597
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Sat Jun 02 01:59:59 CEST 2018
IPC: A61K 38/00
Applicants: AMGEN INC.
Inventors: CHEN, Irwin
CHONG, Su
HARRINGTON, Essa Hu
HONG, Fang-Tsao
LONG, Jason C.
MIRANDA, Leslie P.
Title: PEPTIDE PAC1 ANTAGONISTS
Abstract:
Novel peptides that bind to human PAC1 are provided. These peptides that are antagonists of PAC1 are useful in a number of PAC1 related disorders, including the treatment and/or prevention of headache disorders, including migraine, such as acute migraine.