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1. (WO2018222954) METHODS AND COMPOSITIONS FOR TREATING EXCESSIVE SLEEPINESS

Pub. No.:    WO/2018/222954    International Application No.:    PCT/US2018/035532
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Sat Jun 02 01:59:59 CEST 2018
IPC: A61K 9/20
A61K 31/27
A61K 31/165
A61P 25/00
Applicants: JAZZ PHARMACEUTICALS INTERNATIONAL III LIMITED
CARTER, Lawrence Patrick
LU, Yuan
Inventors: CARTER, Lawrence Patrick
LU, Yuan
Title: METHODS AND COMPOSITIONS FOR TREATING EXCESSIVE SLEEPINESS
Abstract:
The present invention relates to carbamoyl phenylalaninol compounds and methods of using the same to treat disorders. The invention further relates to the development of methods for treating excessive sleepiness in a subject, e.g., due to narcolepsy or obstructive sleep apnea, with the surprising outcome that "normal" levels of wakefulness are achieved based on standard objective and subjective sleepiness tests.