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1. (WO2018222874) METHODS AND DEVICES FOR THE TREATMENT OF FOOD ALLERGIES

Pub. No.:    WO/2018/222874    International Application No.:    PCT/US2018/035399
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Fri Jun 01 01:59:59 CEST 2018
IPC: A61K 39/35
A61K 39/39
A61M 5/158
A61P 37/00
A61P 37/02
Applicants: TEXAS TECH UNIVERSITY SYSTEM
Inventors: GILL, Harvinder, Singh
SHAKYA, Akhilesh, K.
Title: METHODS AND DEVICES FOR THE TREATMENT OF FOOD ALLERGIES
Abstract:
Methods and devices are provided for treating a food allergy in a subject in need thereof. The method entails delivering an effective amount of an allergen associated with the food allergy into the subject's cutis skin layer. Delivering the allergen is carried out by inserting one or more allergen-coated solid microneedles into the subject's skin. The one or more solid microneedles each has a base, shaft and tip, and when inserted in the subject, do not extend beyond the cutis. The allergen is allowed to dissociate from the one or more microneedles while inserted in the subject's cutis. Once the allergen disassociates, the one or more microneedles is removed from the subject's skin.