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1. (WO2018222874) METHODS AND DEVICES FOR THE TREATMENT OF FOOD ALLERGIES
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Pub. No.: WO/2018/222874 International Application No.: PCT/US2018/035399
Publication Date: 06.12.2018 International Filing Date: 31.05.2018
IPC:
A61K 39/35 (2006.01) ,A61K 39/39 (2006.01) ,A61M 5/158 (2006.01) ,A61P 37/00 (2006.01) ,A61P 37/02 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
35
Allergens
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
39
characterised by the immunostimulating additives, e.g. chemical adjuvants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
5
Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
14
Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
158
Needles
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
02
Immunomodulators
Applicants:
TEXAS TECH UNIVERSITY SYSTEM [US/US]; Office of Research Commercialization P.O. Box 42007 Lubbock, TX 79409-2007, US
Inventors:
GILL, Harvinder, Singh; US
SHAKYA, Akhilesh, K.; US
Agent:
CHALKER, Daniel, J.; US
FLORES, Edwin, S.; Chalker Flores, LLP 14951 North Dallas Parkway, Suite 400 Dallas, TX 75254, US
Priority Data:
62/512,88431.05.2017US
62/576,17624.10.2017US
Title (EN) METHODS AND DEVICES FOR THE TREATMENT OF FOOD ALLERGIES
(FR) MÉTHODES ET DISPOSITIFS POUR LE TRAITEMENT D'ALLERGIES ALIMENTAIRES
Abstract:
(EN) Methods and devices are provided for treating a food allergy in a subject in need thereof. The method entails delivering an effective amount of an allergen associated with the food allergy into the subject's cutis skin layer. Delivering the allergen is carried out by inserting one or more allergen-coated solid microneedles into the subject's skin. The one or more solid microneedles each has a base, shaft and tip, and when inserted in the subject, do not extend beyond the cutis. The allergen is allowed to dissociate from the one or more microneedles while inserted in the subject's cutis. Once the allergen disassociates, the one or more microneedles is removed from the subject's skin.
(FR) L'invention concerne des méthodes et des dispositifs pour le traitement d'une allergie alimentaire chez un sujet en ayant besoin. Le procédé consiste à administrer une quantité efficace d'un allergène associé à l'allergie alimentaire dans la couche dermique de la peau du sujet. L'administration de l'allergène est réalisée par introduction d'une ou plusieurs micro-aiguilles solides revêtues d'allergène dans la peau du sujet. La ou les micro-aiguilles solides ont chacune un embout, une tige et une pointe, et lorsqu'elles sont introduites chez le sujet, elles ne vont pas au-delà du derme. L'allergène est amené à se dissocier de la ou des micro-aiguilles lors de son/leur introduction dans le derme du sujet. Une fois l'allergène dissocié, la ou les micro-aiguilles sont retirées de la peau du sujet.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)