Search International and National Patent Collections

1. (WO2018222713) SUBLINGUAL FORMULATION WITH WATER-SOLUBLE COCRYSTALS OF ACETYLSALICYLIC ACID WITH CITRIC ACID, SODIUM BICARBONATE, AND L-THEANINE FOR THE TREATMENT OF ACUTE MYOCARDIAL INFARCTION

Pub. No.:    WO/2018/222713    International Application No.:    PCT/US2018/035127
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Thu May 31 01:59:59 CEST 2018
IPC: A61K 31/616
A61K 9/14
A61K 9/20
A61K 31/12
A61K 31/60
A61K 45/06
Applicants: THEAPRIN PHARMACEUTICALS, INC.
Inventors: FELICE, Philip, V.
BRITTAIN, Harry, G.
Title: SUBLINGUAL FORMULATION WITH WATER-SOLUBLE COCRYSTALS OF ACETYLSALICYLIC ACID WITH CITRIC ACID, SODIUM BICARBONATE, AND L-THEANINE FOR THE TREATMENT OF ACUTE MYOCARDIAL INFARCTION
Abstract:
A water-soluble aspirin, citric acid, sodium bicarbonate, L-theanine cocrystal composition which includes a quantity of acetylsalicylic acid is described. The composition may be created by a method including various steps, including a cocrystallization step. The water- soluble cocrystal composition is suitable for sublingual administration, preferably to humans.