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1. (WO2018222711) COMPOSITIONS COMPRISING A COMBINATION OF AN ANTI-LAG-3 ANTIBODY, A PD-1 PATHWAY INHIBITOR, AND AN IMMUNOTHERAPEUTIC AGENT

Pub. No.:    WO/2018/222711    International Application No.:    PCT/US2018/035125
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Thu May 31 01:59:59 CEST 2018
IPC: C07K 16/28
A61K 39/395
A61K 39/00
A61P 35/00
Applicants: BRISTOL-MYERS SQUIBB COMPANY
Inventors: KORMAN, Alan J.
LONBERG, Nils
SELBY, Mark J.
JACKSON, Jeffrey
Title: COMPOSITIONS COMPRISING A COMBINATION OF AN ANTI-LAG-3 ANTIBODY, A PD-1 PATHWAY INHIBITOR, AND AN IMMUNOTHERAPEUTIC AGENT
Abstract:
Provided are methods for clinical treatment of malignant tumors (e.g., advanced solid tumors) using a combination of an anti-LAG-3 antibody, an anti-PD-1 antibody, and an immunotherapeutic agent.