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1. (WO2018222599) UTILIZING THE INNATE IMMUNE SYSTEM TO DELIVER THERAPEUTIC AGENTS
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Pub. No.: WO/2018/222599 International Application No.: PCT/US2018/034906
Publication Date: 06.12.2018 International Filing Date: 29.05.2018
IPC:
A61K 31/4045 (2006.01) ,A61K 31/41 (2006.01) ,A61K 39/39 (2006.01)
[IPC code unknown for A61K 31/4045][IPC code unknown for A61K 31/41][IPC code unknown for A61K 39/39]
Applicants:
SPILLER, Kara L. [US/US]; US (US)
WOFFORD, Kathryn L. [US/US]; US (US)
DREXEL UNIVERSITY [US/US]; 3141 Chestnut Street Philadelphia, Pennsylvania 19104, US (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BN, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IR, IS, IT, JO, JP, KE, KG, KH, KM, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW)
Inventors:
SPILLER, Kara L.; US
WOFFORD, Kathryn L.; US
Agent:
DOYLE, Kathryn; US
ARNOLD, Gianna Julian; US
CROTTY, Justin W.; US
EDDE, Chantal; US
KUO, Joseph; US
LANDRY, Brian R.; US
LAURO, Peter C.; US
MANAS, Michael G.; US
PLEHN-DUJOWICH, Debora; US
SILVA, Domingos J.; US
SIMPSON, Mark D.; US
TRUJILLO, Doreen Yatko; US
YOUNG, Jacque C.; US
Priority Data:
62/512,28430.05.2017US
Title (EN) UTILIZING THE INNATE IMMUNE SYSTEM TO DELIVER THERAPEUTIC AGENTS
(FR) UTILISATION DU SYSTÈME IMMUNITAIRE INNÉ POUR L'ADMINISTRATION D'AGENTS THÉRAPEUTIQUES
Abstract:
(EN) In one aspect, the invention provides a composition comprising at least one monocyte comprising an agent that increases monocyte homing to a site of injury, and an effective amount of a drug. In another aspect, the invention provides a method of using the composition to deliver a drug to a site of injury.
(FR) Selon un aspect, l'invention concerne une composition comprenant au moins un monocyte comprenant un agent qui augmente la mobilité des monocytes vers un site de lésion, et une quantité efficace d'un médicament. Selon un autre aspect, l'invention concerne une méthode d'utilisation de la composition pour administrer un médicament vers un site de lésion.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)