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1. (WO2018222550) TANGENTIAL FLOW FILTRATION DEVICE FOR PERFUSION APPLICATIONS
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Pub. No.: WO/2018/222550 International Application No.: PCT/US2018/034709
Publication Date: 06.12.2018 International Filing Date: 25.05.2018
IPC:
C12M 1/00 (2006.01) ,B01D 63/10 (2006.01) ,C07K 1/34 (2006.01) ,C12M 1/26 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1
Apparatus for enzymology or microbiology
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
63
Apparatus in general for separation processes using semi-permeable membranes
10
Spiral-wound membrane modules
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
1
General processes for the preparation of peptides
14
Extraction; Separation; Purification
34
by filtration, ultrafiltration or reverse osmosis
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1
Apparatus for enzymology or microbiology
26
Inoculator or sampler
Applicants:
EMD MILLIPORE CORPORATION [US/US]; 400 Summit Drive Burlington, MA 01803, US
Inventors:
DUPONT, Alison; US
Agent:
BALICKY, Eric, M.; US
CARROLL, Alice, O.; US
WAKIMURA, Mary, Lou; US
BROOK, David, E.; US
SMITH, James, M.; US
Priority Data:
62/513,79301.06.2017US
Title (EN) TANGENTIAL FLOW FILTRATION DEVICE FOR PERFUSION APPLICATIONS
(FR) DISPOSITIF DE FILTRATION À ÉCOULEMENT TANGENTIEL POUR DES APPLICATIONS DE PERFUSION
Abstract:
(EN) Filter elements (20, 100) for perfusion systems and methods are provided. A filter element sheet includes a microporous membrane (63, 112) having a mean pore size of at least about 0.65µm and a feed spacer (25, 120) comprising woven fibers and having an open area of at least about 35%. The filter element sheet can be arranged within a filter element, for example, in a spiral-wound format or in a cassette format. A perfusion system includes at least one filter element and a pump configured to control flow of a liquid feed through the at least one filter element.
(FR) L'invention concerne des éléments de filtres (20, 100) pour des systèmes et des procédés de perfusion. Une feuille d'élément de filtre comprend une membrane microporeuse (63, 112) ayant une taille de pore moyenne d'au moins environ 0,65µm et un espaceur d'alimentation (25, 120) comprenant des fibres tissées et ayant une zone ouverte d'au moins environ 35 %. La feuille d'élément de filtre peut être disposée à l'intérieur d'un élément de filtre, par exemple, dans un format enroulé en spirale ou dans un format de cassette. Un système de perfusion comprend au moins un élément de filtre et une pompe conçue pour réguler l'écoulement d'une alimentation de liquide à travers le ou les éléments de filtre.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)