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1. (WO2018222461) METHODS OF DIAGNOSING INTERVERTEBRAL DISC DISEASE AND CHONDRODYSTROPHY IN CANINES
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Pub. No.: WO/2018/222461 International Application No.: PCT/US2018/034135
Publication Date: 06.12.2018 International Filing Date: 23.05.2018
IPC:
C07K 14/50 (2006.01) ,C12Q 1/68 (2018.01)
[IPC code unknown for C07K 14/50][IPC code unknown for C12Q 1/68]
Applicants:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street 12th Floor Oakland, California 94607-5200, US
Inventors:
BANNASCH, Danika; US
BROWN, Emily; US
DICKINSON, Peter J.; US
Agent:
GUEDELHOEFER, Otto C.; US
Priority Data:
62/512,68930.05.2017US
Title (EN) METHODS OF DIAGNOSING INTERVERTEBRAL DISC DISEASE AND CHONDRODYSTROPHY IN CANINES
(FR) MÉDTHODES DE DIAGNOSTIC DE LA MALADIE DU DISQUE INTERVERTÉBRAL ET DE LA CHONDRODYSTROPHIE CHEZ LES CANINS
Abstract:
(EN) Provided are compositions and methods for identifying a canine suffering from or at risk of suffering from skeletal dysplasia (SD) and/or intervertebral disc disease (IVDD) by detecting a retrogene insertion encoding canine fibroblast growth factor 4 (FGF4) on canine chromosome 12.
(FR) L'invention concerne des compositions et des méthodes permettant d'identifier un canin atteint ou risquant d'être atteint d'une dysplasie squelettique (SD) et/ou d'une maladie du disque intervertébral (IVDD), par détection d'une insertion de rétrogène codant pour le facteur 4 de croissance de fibroblastes (FGF4) canin sur le chromosome 12 canin.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)