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1. (WO2018222340) TRIGGERING OF PAYLOAD RELEASE FROM MINIATURIZED DEVICES
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Pub. No.: WO/2018/222340 International Application No.: PCT/US2018/030953
Publication Date: 06.12.2018 International Filing Date: 03.05.2018
IPC:
A61M 37/00 (2006.01) ,A61K 41/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
37
Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
41
Medicinal preparations obtained by treating materials with wave energy or particle radiation
Applicants:
SHPIGELMACHER, Michael [IL/US]; US
BIONAUT LABS LTD. [IL/IL]; 1 Arie Shenkar Street 4672514 Herzliya, IL
Inventors:
SHPIGELMACHER, Michael; US
KISELYOV, Alex; US
Agent:
COHEN, Mark; US
PEARL COHEN ZEDEK LATZER BARATZ LLP; PEARL COHEN ZEDEK LATZER BARATZ LLP 1500 Broadway, 12th Floor New York, New York 10036, US
Priority Data:
62/512,09129.05.2017US
Title (EN) TRIGGERING OF PAYLOAD RELEASE FROM MINIATURIZED DEVICES
(FR) DÉCLENCHEMENT DE LIBÉRATION DE CHARGE UTILE À PARTIR DE DISPOSITIFS MINIATURISÉS
Abstract:
(EN) A carrier device and methods of use are described. The device and methods are directed toward implanting in biological tissue and optionally for propelling in a biological tissue and for releasing a medical payload in a biological tissue according to remote trigger. The carrier device includes at least one element sensitive to the external stimuli. When external stimuli are sent through the tissue, the responsive element provides release of the functional material. In some embodiments, payload release can be started, stopped, and restarted at a later time or place. Individual carrier devices can be selectively triggered by implementing different elements in the devices, each element is sensitive to different stimuli. In addition to payload release, devices of this invention are equipped with a propelling element, the propelling element is responsive to external stimuli that enables propulsion and navigation of the device.
(FR) L'invention concerne un dispositif de support et des procédés d'utilisation. Le dispositif et les procédés concernent l'implantation dans un tissu biologique et, éventuellement, la propulsion dans un tissu biologique et la libération d'une charge utile médicale dans un tissu biologique selon un déclencheur à distance. Le dispositif de support comprend au moins un élément sensible aux stimuli externes. Lorsque des stimuli externes sont envoyés à travers le tissu, l'élément sensible réalise la libération du matériau fonctionnel. Dans certains modes de réalisation, la libération de charge utile peut être démarrée, arrêtée et redémarrée à un moment ou lieu ultérieur. Des dispositifs de support individuels peuvent être sélectivement déclenchés par la mise en œuvre de différents éléments dans les dispositifs, chaque élément étant sensible à différents stimuli. En plus de la libération de charge utile, les dispositifs de l'invention sont équipés d'un élément de propulsion, l'élément de propulsion étant sensible aux stimuli externes qui permettent la propulsion et la navigation du dispositif.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)