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1. (WO2018222069) PROTEIN MARKER FOR DIAGNOSING PROSTATE CANCER, METHOD FOR MEASURING THE QUANTITY OF A MARKER AND ALGORITHM FOR INTERPRETING THE RESULT

Pub. No.:    WO/2018/222069    International Application No.:    PCT/RU2017/000386
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Sat Jun 03 01:59:59 CEST 2017
IPC: G01N 33/574
C07K 16/28
Applicants: LIMITED LIABILITY COMPANY "PROSTAGNOST"
ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ПРОСТАГНОСТ"
Inventors: ZEMSKOVA, Marina Yurievna
ЗЕМСКОВА, Марина Юрьевна
Title: PROTEIN MARKER FOR DIAGNOSING PROSTATE CANCER, METHOD FOR MEASURING THE QUANTITY OF A MARKER AND ALGORITHM FOR INTERPRETING THE RESULT
Abstract:
The invention relates to the field of biology and medicine, specifically to oncology, and can be used for diagnosing prostate cancer. Use is made for this purpose of a novel prostate-cancer marker which can be identified in the undiluted urine of a patient and constitutes integrin-alpha V or a fragment thereof. A method of diagnosing prostate cancer, comprising identifying integrin-alpha V in the undiluted urine of a patient, and a kit for carrying out the diagnosis, comprising at least one antibody specific to integrin-alpha V, or a functional fragment thereof, are also proposed. The invention makes it possible to carry out a non-invasive diagnosis of prostate cancer using a simple, sensitive and reliable method which can be used under standard clinical laboratory conditions in inpatient or outpatient medical institutions.