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1. (WO2018221966) PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF BONE-RELATED DISEASE

Pub. No.:    WO/2018/221966    International Application No.:    PCT/KR2018/006174
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Thu May 31 01:59:59 CEST 2018
IPC: A61K 31/575
A23L 33/10
A61K 31/352
A61K 31/18
A61P 15/12
Applicants: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
연세대학교 산학협력단
Inventors: SEO, Jung Teak
서정택
MOON, Seok Jun
문석준
KIM, Sung Jin
김성진
Title: PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF BONE-RELATED DISEASE
Abstract:
The present invention relates to a pharmaceutical composition for prevention or treatment of bone-related diseases, which promotes the differentiation of preosteoblasts into osteoblasts to induce the formation of calcified nodules and simultaneously suppresses the differentiation of myelocytes into osteoclasts and the function of osteoclasts, thereby effectively controlling bone homeostasis and being very useful for prevention or treatment of bone-related diseases. In addition, the present invention relates to a pharmaceutical composition for prevention or treatment of menopausal diseases, particularly menopausal bone diseases, wherein the pharmaceutical composition increases the volume of spongy bone and promotes the differentiation of preosteoblasts into osteoblasts to induce the formation of calcified nodules and simultaneously suppresses the differentiation of myelocytes into osteoclasts and the function of osteoclasts, thereby effectively controlling bone homeostasis and being very useful for prevention or treatment of menopausal bone-related diseases.