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1. (WO2018221823) MATRIX OF RICE HUSK SILICA FOR IMMOBILIZING ENZYME AND USES THEREOF

Pub. No.:    WO/2018/221823    International Application No.:    PCT/KR2018/000812
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Thu Jan 18 00:59:59 CET 2018
IPC: C12N 11/14
C12P 7/64
C01B 33/12
Applicants: ICOSATECH INC.
Inventors: HAN, Ok Soo
HAN, Chong Soo
LE, Bao Thu
NGIN, Putheary
Title: MATRIX OF RICE HUSK SILICA FOR IMMOBILIZING ENZYME AND USES THEREOF
Abstract:
The present invention relates to a preparation method of a matrix of rice husk silica for immobilizing enzyme wherein a rice husk silica is modified with APTES((3-aminopropyl)triethoxysilane) and glutaraldehyde, a matrix of rice husk silica for immobilizing enzyme prepared by said method, a rice husk silica-enzyme complex wherein enzyme is immobilized onto said matrix of rice husk silica and a preparation method of valuable substances using said rice husk silica-enzyme complex. The rice husk silica having a nanoporous structure cannot only facilitate diffusion of substrate during enzyme reaction but also can be utilized as a path through which intermediates from the consecutive enzyme reactions can travel. Therefore, it can be effectively utilized in preparing valuable substances.