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1. (WO2018221729) AGENT FOR PREVENTING OR TREATING BRAIN ATROPHY

Pub. No.:    WO/2018/221729    International Application No.:    PCT/JP2018/021223
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Sat Jun 02 01:59:59 CEST 2018
IPC: A61K 31/397
A61P 25/28
Applicants: FUJIFILM TOYAMA CHEMICAL CO., LTD.
富士フイルム富山化学株式会社
Inventors: KOBAYASHI Hiroshi
小林 博
MATSUMOTO Yoshihiko
松本 喜彦
Title: AGENT FOR PREVENTING OR TREATING BRAIN ATROPHY
Abstract:
The present invention addresses the problem of providing a chemical agent for suppressing the progression of Alzheimer-type dementia and a method for suppressing the progression of Alzheimer-type dementia. 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof has an effect of suppressing brain atrophy, and is useful as a prophylactic or therapeutic agent for brain atrophy. Thus, it is possible to prevent or treat brain atrophy observed in the aging process or in neurodegenerative diseases by administering 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof.