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1. (WO2018221679) 6H-THIENO[2,3-E][1,2,4]TRIAZOLO[3,4-C][1,2,4]TRIAZEPINE DERIVATIVE

Pub. No.:    WO/2018/221679    International Application No.:    PCT/JP2018/021040
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Fri Jun 01 01:59:59 CEST 2018
IPC: C07D 495/14
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Applicants: AYUMI PHARMACEUTICAL CORPORATION
あゆみ製薬株式会社
Inventors: AONO Hiroyuki
青野 浩之
SEKI Iwao
關 巖
IMAMURA Miwa
今村 美和
TANAKA Tomomi
田中 友美
SHIRAE Satoshi
白江 哲
KAWASHIMA Kenji
川島 健二
YAMAZAKI Yusuke
山崎 裕輔
YAMAMOTO Minoru
山本 実
Title: 6H-THIENO[2,3-E][1,2,4]TRIAZOLO[3,4-C][1,2,4]TRIAZEPINE DERIVATIVE
Abstract:
This 6H-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,2,4]triazepine derivative or a salt thereof has BRD4 inhibitory activity and is therefore useful as a drug, especially as an agent to prevent and/or treat diseases involving BRD4.