Search International and National Patent Collections

1. (WO2018221550) DEMENTIA THERAPEUTIC AGENT COMBINING PYRAZOLOQUINOLINE DERIVATIVE AND MEMANTINE

Pub. No.:    WO/2018/221550    International Application No.:    PCT/JP2018/020649
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Thu May 31 01:59:59 CEST 2018
IPC: A61K 31/4745
A61K 31/13
A61P 25/28
A61P 43/00
Applicants: EISAI R&D MANAGEMENT CO., LTD.
エーザイ・アール・アンド・ディー・マネジメント株式会社
Inventors: MIYAMOTO Mai
宮本 舞
KOTANI Sadaharu
小谷 定治
Title: DEMENTIA THERAPEUTIC AGENT COMBINING PYRAZOLOQUINOLINE DERIVATIVE AND MEMANTINE
Abstract:
Provided is a therapeutic agent for Alzheimer's disease. The therapeutic agent combines: (I) (S)-7-(2-methoxy-3,5-dimethylpyridin-4-yl)-1-(tetrahydrofuran-3-yl)-1H-pyrazolo[4,3-c]quinolin-4(5H)-one, which is represented by formula (I), or a pharmaceutically acceptable salt thereof; and (II) memantine, which is represented by formula (II), or a pharmaceutically acceptable salt thereof.