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1. (WO2018220742) SAMPLE PLATE FOR PESI ION SOURCE AND MASS SPECTROMETER USING SAID SAMPLE PLATE

Pub. No.:    WO/2018/220742    International Application No.:    PCT/JP2017/020253
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Thu Jun 01 01:59:59 CEST 2017
IPC: G01N 27/62
H01J 49/04
Applicants: SHIMADZU CORPORATION
株式会社島津製作所
Inventors: MURATA, Tasuku
村田 匡
UCHIDA, Takeshi
内田 剛史
OGATA, Koretsugu
緒方 是嗣
Title: SAMPLE PLATE FOR PESI ION SOURCE AND MASS SPECTROMETER USING SAID SAMPLE PLATE
Abstract:
This sample plate for a solid sample comprises a plate-like body (2) and a lid (3). The body (2) has a recess (21) that has a bottom surface center that protrudes in a cylindrical shape so as to form a sample stage (21a). The lid (3) has a funnel-shaped opening (31) formed therein directly above the recess (21) such that the diameter of the bottom of the opening is roughly the same as the diameter of the sample stage. When a biological tissue section or other sample (7) is accommodated in the recess (21) and the lid (3) is closed, the bottom surface wall around the opening (31) of the lid (3) pushes the sample (7) down and the sample (7) is sandwiched between the bottom surface wall and sample stage (21a). A solvent for ionization is injected into the opening (31), which has had the bottom thereof blocked by the sample (7). During measurement, a probe (106) is lowered so as to pierce the sample (7), and when the probe (106) is raised, the solvent adheres to the sample adhered to the leading end of the probe (106). According to this configuration, it is possible to repeatedly insert the probe at the same position in a state where the sample is fixed, and because a sufficient amount of solvent adheres to the sample, sufficient ionization is achieved.