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1. (WO2018220583) PRODUCTION OF CYCLIC ADENYLATES AND THEIR USE AS ALLOSTERIC REGULATORS
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Pub. No.: WO/2018/220583 International Application No.: PCT/IB2018/053906
Publication Date: 06.12.2018 International Filing Date: 31.05.2018
IPC:
C12N 9/22 (2006.01) ,C07H 21/00 (2006.01)
[IPC code unknown for C12N 9/22][IPC code unknown for C07H 21]
Applicants:
VILNIUS UNIVERSITY [LT/LT]; Universiteto g. 3 LT-01513 Vilnius, LT
Inventors:
ŠIKŠNYS, Virginijus; LT
KAZLAUSKIENĖ, Miglė; LT
TAMULAITIS, Gintautas; LT
KOSTIUK, Georgij; LT
Agent:
PETNIŪNAITĖ, Jurga; LT
Priority Data:
62/512,86831.05.2017US
Title (EN) PRODUCTION OF CYCLIC ADENYLATES AND THEIR USE AS ALLOSTERIC REGULATORS
(FR) PRODUCTION D'ADÉNYLATES CYCLIQUES ET LEUR UTILISATION EN TANT QUE RÉGULATEURS ALLOSTÉRIQUES
Abstract:
(EN) A method of synthetizing cyclic oligoadenylates using a novel catalytic activity of a protein possessing the Palm domain, such as the Cas10 protein, and using such compounds for activation of proteins possessing the CARF doman, such as the Csm6 protein.
(FR) L'invention concerne un procédé de synthèse d'oligoadénylates cycliques à l'aide d'une nouvelle activité catalytique d'une protéine possédant le domaine paume, telle que la protéine Cas10, et l'utilisation de tels composés pour l'activation de protéines possédant le domaine CARF, telle que la protéine Csm6.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)