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1. (WO2018220514) WATER-SOLUBLE POLYSACCHARIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USES
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Pub. No.: WO/2018/220514 International Application No.: PCT/IB2018/053790
Publication Date: 06.12.2018 International Filing Date: 29.05.2018
IPC:
A61K 47/36 (2006.01) ,A61K 31/722 (2006.01) ,C08B 37/08 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
715
Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
716
Glucans
722
Chitin; Chitosan
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
B
POLYSACCHARIDES; DERIVATIVES THEREOF
37
Preparation of polysaccharides not provided for in groups C08B1/-C08B35/110; Derivatives thereof
08
Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
Applicants:
JOINTHERAPEUTICS SRL [IT/IT]; Piazza del Popolo, 1 22100 Como, IT
Inventors:
BIANCHINI, Giulio; IT
CALLEGARO, Lanfranco; IT
Agent:
ADV IP S.R.L.; Corso di Porta Vittoria 29 20122 Milano, IT
Priority Data:
10201700006053001.06.2017IT
Title (EN) WATER-SOLUBLE POLYSACCHARIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USES
(FR) DÉRIVÉS DE POLYSACCHARIDES HYDROSOLUBLES, LEUR PROCÉDÉ DE PRÉPARATION ET LEURS UTILISATIONS
Abstract:
(EN) A neutral salt consisting of a polyaminosaccharide cation and an anion, as well as a procedure for the preparation of the neutral salt and uses thereof as a biomaterial and as an ingredient in pharmaceutical compositions are disclosed. Indeed, said neutral salt has surprisingly exhibited high water- solubility and high purity, the preparation procedure having minimised the content of high-risk contaminants in the final product and reduced reaction and purification times.
(FR) L'invention concerne un sel neutre constitué d'un cation polyaminosaccharide et d'un anion, ainsi qu'un procédé de préparation du sel neutre et ses utilisations à titre de biomatériau et d'ingrédient dans des compositions pharmaceutiques. En effet, ledit sel neutre présente contre toute attente une solubilité élevée dans l'eau et une pureté élevée, son procédé de préparation ayant réduit au minimum la teneur en contaminants à haut risque dans le produit final et des temps de réaction et de purification réduits.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: Italian (IT)