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1. (WO2018220446) TRIPLE COMBINATION ANTIBODY THERAPIES

Pub. No.:    WO/2018/220446    International Application No.:    PCT/IB2018/000696
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Sat Jun 02 01:59:59 CEST 2018
IPC: A61K 39/395
C07K 16/28
Applicants: COMPUGEN LTD.
Inventors: LIANG, Spencer
LEUNG, Ling
WHELAN, Sarah
KOTTURI, Maya
MACHLENKIN, Arthur
OPHIR, Eran
ALTEBER, Zoya
AZULAY, Meir
LOGRONIO, Kathryn
KUMAR, Sandeep
DESAI, Radhika
CHAN, Christopher
Title: TRIPLE COMBINATION ANTIBODY THERAPIES
Abstract:
The present invention is directed to triple combination therapies with anti-TIGIT antibodies, anti-PVRIG antibodies, and checkpoint inhibitors, including anti-PD-1 or anti- PD-L1 antibodies.