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1. (WO2018220390) SYNCYTIOTROPHOBLAST EXTRACELLULAR VESICLES AS BIOMARKER FOR GESTATIONAL DIABETES MELLITUS
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Pub. No.: WO/2018/220390 International Application No.: PCT/GB2018/051500
Publication Date: 06.12.2018 International Filing Date: 01.06.2018
IPC:
G01N 33/50 (2006.01) ,G01N 33/68 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
Applicants:
OXFORD UNIVERSITY INNOVATION LIMITED [GB/GB]; Buxton Court 3 West Way Botley Oxford OX2 OJB, GB
Inventors:
VATISH, Manu; GB
SARGENT, Ian; GB
KANDZIJA, Neva; GB
ZHANG, Wei; GB
TANNETTA, Dionne; GB
Agent:
BARKER BRETTELL LLP; 100 Hagley Road Edgbaston Birmingham West Midlands B16 8QQ, GB
Priority Data:
1708741.201.06.2017GB
Title (EN) SYNCYTIOTROPHOBLAST EXTRACELLULAR VESICLES AS BIOMARKER FOR GESTATIONAL DIABETES MELLITUS
(FR) VÉSICULES EXTRACELLULAIRES DE SYNCYTIOTROPHOBLASTE EN TANT QUE BIOMARQUEUR POUR LE DIABÈTE SUCRÉ GESTATIONNEL
Abstract:
(EN) The present invention relates to a method of determining the gestational diabetic status of a pregnant subject, comprising providing a biological sample obtained from the subject; and determining the presence, and/or level, of syncytiotrophoblast extracellular vesicles, and/or insulin receptor, and/or DPPIV in the biological sample.
(FR) La présente invention concerne un procédé de détermination de l'état diabétique gestationnel d'une femme enceinte, comprenant la fourniture d'un échantillon biologique obtenu à partir du sujet ; et la détermination de la présence, et/ou de la teneur, de vésicules extracellulaires de syncytiotrophoblaste et/ou du récepteur de l'insuline, et/ou de la DPPIV dans l'échantillon biologique.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)