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1. (WO2018220253) CARBOXYLIC ACID DERIVATIVES OF PYRIDOQUINAZOLINES USEFUL AS PROTEIN KINASE INHIBITORS

Pub. No.:    WO/2018/220253    International Application No.:    PCT/ES2018/070397
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Fri Jun 01 01:59:59 CEST 2018
IPC: C07D 471/04
A61P 17/06
A61K 31/517
Applicants: ONCOSTELLAE, S.L.
Inventors: KURZ, Guido
CAMACHO GÓMEZ, Juan
Title: CARBOXYLIC ACID DERIVATIVES OF PYRIDOQUINAZOLINES USEFUL AS PROTEIN KINASE INHIBITORS
Abstract:
The present invention relates to novel carboxylic acid derivatives of 11-oxo-11H-pyrido [2,1-b]quinazoline-6-carboxamide as potent inhibitors of protein kinase, to pharmaceutical compositions containing them and to the use of said compounds for the manufacture of a medicament for the treatment of pathological conditions or diseases which can be improved by the inhibition of protein kinase.