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|1. (WO2018220225) AGGRECAN BINDING IMMUNOGLOBULINS|
MERCK PATENT GMBH
|Title:||AGGRECAN BINDING IMMUNOGLOBULINS|
The present invention relates to immunoglobulins that specifically bind Aggrecan and more in particular to polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the immunoglobulins of the present invention inhibit the activity of Aggrecan.