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1. (WO2018220185) NOVEL CIRCULAR RNA BIOMARKERS FOR HEART FAILURE

Pub. No.:    WO/2018/220185    International Application No.:    PCT/EP2018/064487
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Sat Jun 02 01:59:59 CEST 2018
IPC: C12Q 1/68
C12N 15/113
Applicants: LUXEMBOURG INSTITUTE OF HEALTH (LIH)
Inventors: DEVAUX, Yvan
ZHANG, Lu
Title: NOVEL CIRCULAR RNA BIOMARKERS FOR HEART FAILURE
Abstract:
The application discloses circRNAs as new biomarkers for the diagnosis of heart failure, the prediction of the clinical evolution of heart failure and/or prediction of the response to a treatment in a patient; methods for the prediction of outcome and diagnosis of heart failure and/or predicting the response to a treatment are provided based on measuring said one or more circRNAs; and kits and devices for measuring said circRNAs and/or performing said methods. Further provided are methods for treating patients with heart failure based on the evaluation of said one or more circRNAs.