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|1. (WO2018220149) COMPOUNDS|
|Applicants:||F. HOFFMANN-LA ROCHE AG
HOFFMANN-LA ROCHE INC.
C4 THERAPEUTICS, INC.
NAGEL, Yvonne Alice
The present invention provides compounds which are selective allosteric inhibitors of TMLR, TMLRCS, LR, LRCS containing EGFR mutants, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances.