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1. (WO2018220137) ASSEMBLY FOR THE PRODUCTION OF TISSUE IMPLANTS

Pub. No.:    WO/2018/220137    International Application No.:    PCT/EP2018/064371
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Fri Jun 01 01:59:59 CEST 2018
IPC: A61F 2/10
A61L 27/60
B29C 33/40
B29C 33/00
A61L 27/38
Applicants: ETH ZÜRICH
Inventors: FOX, Stephan
HU, Jimmy
Title: ASSEMBLY FOR THE PRODUCTION OF TISSUE IMPLANTS
Abstract:
An injection moulding assembly for the production of tissue implants comprising an inner mould element (1) having a mould cavity and an outer mould element (6) having a restriction cavity, the tissue implant comprising at least a first volume of a first tissue equivalent wherein the inner mould element comprises at least one membrane (3) and the mould cavity of the inner mould element is at least partially delimited by said at least one membrane; wherein the inner mould element comprises a gate opening (10) allowing the injection of a first tissue equivalent precursor into the mould cavity; whereby the outer mould element is configured such as to receive the inner mould element within the restriction cavity and the restriction cavity comprises a rigid wall delimiting at least the part of the restriction cavity facing the membrane delimiting the mould cavity when the inner mould element is received within the restriction cavity and the at least one membrane of the inner mould element is sealed to the inner mould such as to provide a peelable seal, as well as a process for the production of tissue implants using the injection moulding assembly