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1. (WO2018220123) LONG-ACTING GIP PEPTIDE ANALOGUES
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Pub. No.: WO/2018/220123 International Application No.: PCT/EP2018/064355
Publication Date: 06.12.2018 International Filing Date: 31.05.2018
Chapter 2 Demand Filed: 08.10.2018
IPC:
C07K 14/605 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
575
Hormones
605
Glucagons
Applicants:
UNIVERSITY OF COPENHAGEN [DK/DK]; Nørregade 10 1165 Copenhagen K, DK
Inventors:
ROSENKILDE, Mette, Marie; DK
HOLST, Jens, Juul; DK
GASBJERG, Lærke, Smidt; DK
SPARRE-ULRICH, Alexander, Hovard; DK
GABE, Maria, Buur, Nordskov; DK
Agent:
HØIBERG P/S; Adelgade 12 1304 Copenhagen K, DK
Priority Data:
17173628.331.05.2017EP
Title (EN) LONG-ACTING GIP PEPTIDE ANALOGUES
(FR) ANALOGUES PEPTIDIQUES DE GIP À ACTION PROLONGÉE
Abstract:
(EN) Disclosed are glucose-dependent insulinotropic peptide (GIP)-derived peptide analogues GIP5-30 and GIP3-30 which are antagonists of the GIP receptor and comprises at least one fatty acid molecule to increase half-life while maintaining antagonistic properties.
(FR) L'invention concerne des analogues peptidiques dérivés de peptide insulinotrope glucodépendant (GIP) GIP5-30 et GIP3-30 qui sont des antagonistes du récepteur de GIP et comprennent au moins une molécule d'acide gras pour augmenter la demi-vie tout en maintenant des propriétés antagonistes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)