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1. (WO2018219956) CANCER-ASSOCIATED IMMUNOSUPPRESSION INHIBITOR
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Pub. No.: WO/2018/219956 International Application No.: PCT/EP2018/064081
Publication Date: 06.12.2018 International Filing Date: 29.05.2018
IPC:
C07K 16/28 (2006.01)
[IPC code unknown for C07K 16/28]
Applicants:
GAMAMABS PHARMA [FR/FR]; Centre Pierre Potier ONCOPOLE entrée B 1 place Pierre Potier 31106 Toulouse, FR
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM) [FR/FR]; 101, rue de Tolbiac 75013 Paris, FR
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) [FR/FR]; 3, Rue Michel Ange 75016 Paris, FR
UNIVERSITE PARIS DESCARTES [FR/FR]; 12, rue de l'Ecole de Médecine 75006 Paris, FR
Inventors:
BARRET, Jean-Marc; FR
PROST, Jean-François; FR
LAHMAR, Mehdi; FR
DEGOVE, Stéphane; FR
BOUGHERARA, Houcine; FR
DONNADIEU, Emmanuel; FR
Agent:
CABINET NONY; 11 rue Saint-Georges 75009 Paris, FR
Priority Data:
17305619.329.05.2017EP
Title (EN) CANCER-ASSOCIATED IMMUNOSUPPRESSION INHIBITOR
(FR) INHIBITEUR D'IMMUNOSUPPRESSION ASSOCIÉ AU CANCER
Abstract:
(EN) The present invention relates to a glyco-engineered Fc fragment-bearing compound for its use as an immunosuppression inhibitor in the treatment of a cancer-associated immunosuppression. The invention further relates to a pharmaceutical composition comprising at least this glyco-engineered Fc fragment-bearing compound.
(FR) La présente invention concerne un composé porteur de fragment Fc glycomodifié pour son utilisation en tant qu'inhibiteur d'immunosuppression dans le traitement d'une immunosuppression associée au cancer. L'invention concerne en outre une composition pharmaceutique comprenant au moins ce composé porteur de fragment Fc glycomodifié.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)