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1. (WO2018219258) HIGH PERFORMANCE LIQUID CHROMATOGRAPHY FOR FREE MANNOSE AND GLUCOSE IN SERUM
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Pub. No.: WO/2018/219258 International Application No.: PCT/CN2018/088774
Publication Date: 06.12.2018 International Filing Date: 29.05.2018
IPC:
G01N 30/06 (2006.01) ,G01N 30/02 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
30
Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography
02
Column chromatography
04
Preparation or injection of sample to be analysed
06
Preparation
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
30
Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography
02
Column chromatography
Applicants:
青岛大学附属医院 THE AFFILIATED HOSPITAL OF QINGDAO UNIVERSITY [CN/CN]; 中国山东省青岛市 市南区江苏路16号张丽娟 No.16 Jiangsu Road, Shinan District Qigndao, Shandong 266000, CN
Inventors:
张丽娟 ZHANG, Lijuan; CN
刘永 LIU, Yong; CN
Agent:
青岛合创知识产权代理事务所 (普通合伙) QINGDAO HECHUANG INTELLECTUAL PROPERTY AGENCY FIRM (GENERAL PARTNERSHIP ); 中国山东省青岛市 崂山区株洲路20号海信创智谷B座1803室傅培 FU, Pei Room 1803, Building B, Hisense Chuangzhi Valley, 20 Zhuzhou Road, Laoshan District Qingdao, Shandong 266000, CN
Priority Data:
201710394424.429.05.2017CN
Title (EN) HIGH PERFORMANCE LIQUID CHROMATOGRAPHY FOR FREE MANNOSE AND GLUCOSE IN SERUM
(FR) CHROMATOGRAPHIE LIQUIDE HAUTE PERFORMANCE POUR MANNOSE LIBRE ET GLUCOSE DANS LE SÉRUM
(ZH) 血清游离甘露糖和葡萄糖的高效液相色谱检测
Abstract:
(EN) Provided is a high performance liquid chromatography method for free mannose and glucose in serum on the basis of the current situation regarding detection of mannose and glucose within serums in existing technology. The method is applied to the measurement of free glucose and mannose in a serum, so that the pretreatment process of samples is simpler, the detection time is shortened, and the detection efficiency is increased. When detection in serum samples is carried out, mannose, rhamnose and glucose may be completely separated, and mannose and glucose will not affect each other during quantification, thereby ensuring the accuracy of detection results.
(FR) L'invention concerne un procédé de chromatographie liquide à haute performance pour mannose libre et glucose dans le sérum en fonction de la situation en cours concernant la détection de mannose et de glucose dans des sérums dans une technologie existante. Le procédé est appliqué à la mesure de glucose libre et de mannose dans un sérum, de telle sorte que le processus de prétraitement d'échantillons soit simplifié, que le temps de détection soit raccourci, et que l'efficacité de détection soit augmentée. Lorsque la détection dans des échantillons de sérum est effectuée, le mannose, le rhamnose et le glucose peuvent être complètement séparés, et le mannose et le glucose ne s'affecteront pas l'un l'autre pendant la quantification, ce qui permet d'assurer la précision des résultats de détection.
(ZH) 基于现有技术中血清游离甘露糖和葡萄糖检测的现状,提供了一种血清游离甘露糖和葡萄糖的高效液相色谱分析方法,将其应用于测定血清中的游离葡萄糖和甘露糖,使样品的前处理过程更加简单,缩短检测时间,提高检测效率。在检测血清样品时,甘露糖,鼠李糖和葡萄糖可以完全分离,而且甘露糖与葡萄糖在进行定量时相互之间不会产生影响,保证检测结果的准确性。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)