Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2018219045) DECELLULARIZED CORNEAL STROMAL LENS AND PREPARATION METHOD THEREFOR
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/219045 International Application No.: PCT/CN2018/082470
Publication Date: 06.12.2018 International Filing Date: 10.04.2018
IPC:
A61F 2/16 (2006.01) ,A61L 27/36 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
02
Prostheses implantable into the body
14
Eye parts, e.g. lenses, corneal implants; Artificial eyes
16
Intraocular lenses
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
36
containing ingredients of undetermined constitution or reaction products thereof
Applicants:
广州新诚生物科技有限公司 GUANGZHOU SUN-SHING BIOTECH CO., LTD. [CN/CN]; 中国广东省广州市 广州国际生物岛螺旋三路6号第七层701单元 Unit 701, 7th Floor, No. 6 Luoxuan 3rd Road, Guangzhou International Bio-island Guangzhou, Guangdong 510000, CN
Inventors:
梁丽金 LIANG, Lijin; CN
杨习锋 YANG, Xifeng; CN
曾晨光 ZENG, Chenguang; CN
余克明 YU, Keming; CN
庄菁 ZHUANG, Jing; CN
Agent:
北京超凡志成知识产权代理事务所(普通合伙) CHOFN INTELLECTUAL PROPERTY; 中国北京市 海淀区北四环西路68号左岸工社1215-1218室 Room 1215-1218, Floor 12 Left Bank Community No.68 Beisihuanxilu, Haidian District Beijing 100080, CN
Priority Data:
201710403038.731.05.2017CN
Title (EN) DECELLULARIZED CORNEAL STROMAL LENS AND PREPARATION METHOD THEREFOR
(FR) LENTILLE STROMALE CORNÉENNE DÉCELLULARISÉE ET SON PROCÉDÉ DE PRÉPARATION
(ZH) 去细胞角膜基质透镜及其制备方法
Abstract:
(EN) Disclosed are a decellularized corneal stromal lens and a preparation method therefor, which relate to the technical field of tissue engineering. The preparation method for the decellularized corneal stromal lens can not only effectively remove cell components in the stroma and reduce immunogenicity of the corneal stromal lens, but also can increase mechanical strength of the corneal lens, and thus can effectively maintain the original morphology and transparency of the corneal stroma. The prepared corneal stromal lens have the features of higher safety, better transparency, and more stable performance; moreover, said lens can be used as a scaffold for the proliferation and growth of corneal stromal cells, which will finally be integrated with the autologous cornea, allowing said lens to be used as permanent implant lens; in addition, the occurrence of situations such as immunological exclusion can be avoided.
(FR) L'invention concerne une lentille stromale cornéenne décellularisée et son procédé de préparation, qui relèvent du domaine technique de l'ingénierie tissulaire. Le procédé de préparation de la lentille stromale cornéenne décellularisée peut non seulement éliminer efficacement les composants cellulaires dans le stroma et réduire l'immunogénicité de la lentille stromale cornéenne, mais peut également accroître la résistance mécanique de la lentille cornéenne, et peut ainsi maintenir efficacement la morphologie originale et la transparence du stroma cornéen. La lentille cornéenne cornéenne préparée présente les caractéristiques d'une plus grande sécurité, d'une meilleure transparence et d'une performance plus stable ; de plus, ladite lentille peut être utilisée à titre d'échafaudage pour la prolifération et la croissance de cellules stromales cornéennes, qui s'intègreront finalement à la cornée autologue, ce qui permet à ladite lentille d'être utilisée comme une lentille d'implant permanente ; de plus l'occurrence de cas tels que l'exclusion immunologique peut être évitée.
(ZH) 一种去细胞角膜基质透镜及其制备方法,涉及组织工程学的技术领域。该去细胞角膜基质透镜的制备方法不仅能够有效去除基质中细胞成分,降低角膜基质透镜的免疫原性,提高角膜透镜的力学强度,更能有效保持角膜基质的原始形态和透明度,所制得的去细胞角膜基质透镜具有安全性更高、透明度更佳和性能更稳定的特点;而且可以作为角膜基质细胞增殖生长的支架,最终与自体角膜融为一体,可作为永久性植入透镜;另外,还能够避免免疫排斥等现象的出现。
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)