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1. (WO2018218787) THIRD-GENERATION SEQUENCING SEQUENCE CORRECTION METHOD BASED ON LOCAL GRAPH

Pub. No.:    WO/2018/218787    International Application No.:    PCT/CN2017/098120
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Sat Aug 19 01:59:59 CEST 2017
IPC: G06F 19/22
G06F 19/20
Applicants: XIAO, Chuanle
肖传乐
Inventors: XIAO, Chuanle
肖传乐
Title: THIRD-GENERATION SEQUENCING SEQUENCE CORRECTION METHOD BASED ON LOCAL GRAPH
Abstract:
A third-generation sequencing sequence correction method based on a local graph and a system thereof. The system comprises a pairwise alignment module, a multiple-sequence alignment module, a correction operation alignment module, a correction operation classification module, a consistent-area base position correction and complex-area local graph base sequence correction module, and a module-sequence correction division and de-fusion processing module. The pairwise alignment module is separately connected to a single molecule real-time sequencing database and a nanopore sequencing database, and the single molecule real-time sequencing database and the nanopore sequencing database are separately input to the pairwise alignment module. The precision of the method and system can reach 99%, and the speed is 7-10 times that of current application software.