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1. (WO2018218305) METHOD FOR MANUFACTURING A CALCIFIED TISSUE SUBSTITUTE

Pub. No.:    WO/2018/218305    International Application No.:    PCT/AU2018/050541
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Sat Jun 02 01:59:59 CEST 2018
IPC: A61K 6/033
A61K 6/027
A61K 33/10
A61K 33/42
A61L 27/56
A61L 27/12
Applicants: THE UNIVERSITY OF WESTERN AUSTRALIA
Inventors: RUAN, Rui
ZHENG, Ming-Hao
Title: METHOD FOR MANUFACTURING A CALCIFIED TISSUE SUBSTITUTE
Abstract:
The invention relates to a method for manufacturing a calcified tissue substitute, the method comprising: reacting ground nacre, monocalcium phosphate, and water to produce brushite; grinding the brushite; reacting ground nacre with the ground brushite in disodium hydrogenphosphate solution. The invention also relates to a calcified tissue substitute manufactured by the method, use of the calcified tissue substitute for repairing a calcified tissue, and a delivery device for delivering the calcified tissue.