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1. (WO2018218273) METHOD OF TREATING HYPERTENSION AND KIDNEY DISEASE

Pub. No.:    WO/2018/218273    International Application No.:    PCT/AU2017/051169
Publication Date: Fri Dec 07 00:59:59 CET 2018 International Filing Date: Thu Oct 26 01:59:59 CEST 2017
IPC: A61K 38/17
A61P 9/12
A61K 48/00
A61K 39/395
A61K 31/7105
Applicants: PARANTA BIOSCIENCES LIMITED
Inventors: KREPINSKY, Joan
Title: METHOD OF TREATING HYPERTENSION AND KIDNEY DISEASE
Abstract:
The present disclosure provides a method of treating hypertension in a subject suffering from or at risk of developing type 1 diabetes, the method comprising administering to the subject an agent that down-regulates the functional level of activin or up-regulates the functional level of follistatin. The present disclosure also provides a method of treating glomerular hyperfiltration in a subject, the method comprising administering to the subject an agent that down-regulates the functional level of activin or up-regulates the functional level of follistatin.