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1. (WO2018205357) STRUCTURED LIGHT ILLUMINATION MICROSCOPIC IMAGING SYSTEM

Pub. No.:    WO/2018/205357    International Application No.:    PCT/CN2017/089163
Publication Date: Fri Nov 16 00:59:59 CET 2018 International Filing Date: Wed Jun 21 01:59:59 CEST 2017
IPC: G02B 21/06
Applicants: SUZHOU INSTITUTE OF BIOMEDICAL ENGINEERING AND TECHNOLOGY, CHINESE ACADEMY OF SCIENCES
中国科学院苏州生物医学工程技术研究所
Inventors: XIONG, Daxi
熊大曦
YANG, Xibin
杨西斌
WANG, Peipei
王沛沛
Title: STRUCTURED LIGHT ILLUMINATION MICROSCOPIC IMAGING SYSTEM
Abstract:
A structured light illumination microscopic imaging system, comprising: a light beam shaping lens (2), an excitation light filter (3) and a dichroscope (4) sequentially provided on an emission light path of a structured light source (1); an objective lens (5) and a sample (6) sequentially provided on a first light path of the dichroscope (4); and an emission light filter (7), a barrel mirror (8) and a detector (9) sequentially provided on a second light path of the dichroscope (4). Compared with a structured light microscopic imaging system provided with a fly-eye lens, under the premise of the requirement of reducing installation and processing precision of the structured light illumination microscopic imaging system, a super-resolution microscopic image with higher signal-to-noise ratio and contrast can be obtained; compared with a structured light microscopic imaging system based on a digital micro-lens array or an optical grating, the system costs are greatly reduced, and the system stability is higher.