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1. (WO2018205343) CAR.IL-33-T AND PREPARATION AND APPLICATION THEREOF

Pub. No.:    WO/2018/205343    International Application No.:    PCT/CN2017/088506
Publication Date: Fri Nov 16 00:59:59 CET 2018 International Filing Date: Fri Jun 16 01:59:59 CEST 2017
IPC: C12N 5/10
C12N 15/85
C12N 15/62
A61K 35/17
A61P 35/00
Applicants: THE FIRST PEOPLE'S HOSPITAL OF CHANGZHOU
常州市第一人民医院
Inventors: JIANG, Jingting
蒋敬庭
LU, Binfeng
卢斌峰
CHEN, Yu'ang
陈宇昂
CHEN, Lujun
陈陆俊
Title: CAR.IL-33-T AND PREPARATION AND APPLICATION THEREOF
Abstract:
Provided in the present invention are CAR.IL-33-T cells and the preparation and application thereof, relating to the field of biotechnology. The chimeric antigen receptor T cells provided in the present invention express a chimeric antigen receptor (CAR) and interleukin-33 (IL-33) that target tumour antigens.