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1. (WO2018205233) USE OF POLYPEPTIDE COMPOUND IN TREATMENT OF ACUTE PANCREATITIS

Pub. No.:    WO/2018/205233    International Application No.:    PCT/CN2017/084013
Publication Date: Fri Nov 16 00:59:59 CET 2018 International Filing Date: Fri May 12 01:59:59 CEST 2017
IPC: A61K 38/10
A61P 1/18
C07K 7/08
Applicants: SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD.
深圳君圣泰生物技术有限公司
Inventors: LIU, Liping
刘利平
BAI, Ru
白茹
Title: USE OF POLYPEPTIDE COMPOUND IN TREATMENT OF ACUTE PANCREATITIS
Abstract:
Disclosed is the use of an INGAP-PP peptide, an HIP peptide or an analogue thereof in the preparation of a drug for treating acute pancreatitis. The polypeptide compound can significantly reduce the increase in the levels of amylase and lipase in the blood caused by acute pancreatitis, reduce the degree of pancreatic pathological damage caused by pancreatitis, and significantly decrease death caused by acute pancreatitis.