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1. (WO2018205017) FILM DOSAGE FORM WITH EXTENDED RELEASE MUCOADHESIVE PARTICLES

Pub. No.:    WO/2018/205017    International Application No.:    PCT/CA2018/050542
Publication Date: Fri Nov 16 00:59:59 CET 2018 International Filing Date: Wed May 09 01:59:59 CEST 2018
IPC: A61K 9/10
A61K 36/18
A61K 47/06
A61K 9/00
A61K 9/14
Applicants: INTELGENX CORP.
Inventors: OBEID, Rodolphe
PAIEMENT, Nadine
GONZALEZ, Erick
Title: FILM DOSAGE FORM WITH EXTENDED RELEASE MUCOADHESIVE PARTICLES
Abstract:
An orally administered dosage form that facilitates delivery of an agent locally in the buccal cavity for a sustained period of time includes mucoadhesive particles that are made of at least a mucoadhesive material combined with the agent, and which are dispersed in a disintegrating film. The dosage form is capable of delivering an agent to a patient at the desired oral mucosa site over an extended period of time while reducing patient discomfort or annoyance associated with conventional sustained release mucoadhesive films that must reside on the oral mucosa during the period of sustained release.