Search International and National Patent Collections

1. (WO2018204873) MODULAR SELF ASSEMBLY DISASSEMBLY (SADA) TECHNOLOGIES

Pub. No.:    WO/2018/204873    International Application No.:    PCT/US2018/031235
Publication Date: Fri Nov 09 00:59:59 CET 2018 International Filing Date: Sat May 05 01:59:59 CEST 2018
IPC: G01N 33/50
A61K 49/14
Applicants: MEMORIAL SLOAN KETTERING CANCER CENTER
Inventors: SANTICH, Brian H.
AHMED, Mahiuddin
CHEUNG, Nai-Kong V.
Title: MODULAR SELF ASSEMBLY DISASSEMBLY (SADA) TECHNOLOGIES
Abstract:
The present invention relates to compositions and methods employing conjugates that include a self-assembly and disassembly (SADA) polypeptide and a binding domain. The present invention encompasses the recognition that conjugates with a SADA polypeptide have certain improved biological properties. SADA-conjugates are described, along with uses thereof (e.g., as therapeutic or diagnostic agents) and methods of manufacture.