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1. (WO2018204798) GENETICALLY MODIFIED TREHALASE-EXPRESSING YEASTS AND FERMENTATION PROCESSES USING SUCH GENETICALLY MODIFIED YEASTS

Pub. No.:    WO/2018/204798    International Application No.:    PCT/US2018/031110
Publication Date: Fri Nov 09 00:59:59 CET 2018 International Filing Date: Sat May 05 01:59:59 CEST 2018
IPC: C12N 9/00
C12N 9/14
C12N 9/24
Applicants: CARGILL, INCORPORATED
Inventors: JAUERT, Peter, Alan
POYNTER, Gregory, Michael
RUSH, Brian, J.
Title: GENETICALLY MODIFIED TREHALASE-EXPRESSING YEASTS AND FERMENTATION PROCESSES USING SUCH GENETICALLY MODIFIED YEASTS
Abstract:
The present invention relates to genetically engineered yeasts having a heterologous trehalase gene and fermentation processes for using such yeasts. The yeasts can express trehalase in a quantity sufficient to convert significant amounts of trehalose to glucose, thereby improving the yield of the product in a fermentation, and/or reducing or eliminating the need to add exogenous trehalase to the fermentation. The yeasts can also include other heterologous genes for expressing enzymes useful for improving yield and/or for reducing or eliminating the need to add exogenous enzymes to the fermentation.