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1. (WO2018204725) THERANOSTIC TOOLS FOR MANAGEMENT OF PANCREATIC CANCER AND ITS PRECURSORS
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Pub. No.: WO/2018/204725 International Application No.: PCT/US2018/030994
Publication Date: 08.11.2018 International Filing Date: 03.05.2018
IPC:
C12Q 1/68 (2018.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. [US/US]; 12902 Magnolia Dr. Tampa, FL 33612-9497, US
Inventors:
PERMUTH, Jennifer; US
JEONG, Daniel; US
CHOI, Jung; US
BALAGURUNATHAN, Yoganand; US
CHEN, Dung-tsa; US
MALAFA, Mokenge; US
Agent:
LADWIG, Glenn, P.; US
PACE, Doran, R.; US
LLOYD, Jeff; US
EISENSCHENK, Frank, C.; US
SALIWANCHIK, David, R.; US
Priority Data:
62/501,04003.05.2017US
Title (EN) THERANOSTIC TOOLS FOR MANAGEMENT OF PANCREATIC CANCER AND ITS PRECURSORS
(FR) OUTILS THÉRANOSTIQUES POUR LA GESTION DU CANCER DU PANCRÉAS ET DE SES PRÉCURSEURS
Abstract:
(EN) The present invention concerns materials and methods for identifying and classifying pancreatic ductal adenocarcinoma (PDAC) precursors or intraductal papillary mucinous neoplasm (IPMN) using messenger RNAs, microRNAs, long non-coding RNAs, radiomic features, radiologic measures of abdominal/visceral obesity, and combinations thereof, as diagnostic markers for integration with clinical management and interventions for personalized care.
(FR) La présente invention concerne des matériaux et des méthodes d'identification et de classification de précurseurs d'adénocarcinome canalaire pancréatique (PDAC) ou de tumeur intracanalaire papillaire et mucineuse du pancréas (IPMN) en utilisant des ARN messagers, des micro-ARN, des ARN longs non codants, des caractéristiques radiomiques, des mesures radiologiques de l'obésité abdominale/viscérale, et des combinaisons associées, en tant que marqueurs de diagnostic pour une intégration à une gestion clinique et à des interventions pour des soins personnalisés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)