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1. (WO2018204564) THIOSEMICARBAZONE DERIVATIVES AS ANTI-CANCER AGENTS

Pub. No.:    WO/2018/204564    International Application No.:    PCT/US2018/030765
Publication Date: Fri Nov 09 00:59:59 CET 2018 International Filing Date: Fri May 04 01:59:59 CEST 2018
IPC: C07C 337/08
A61K 31/175
A61K 31/30
A61K 31/315
A61P 35/00
Applicants: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
Inventors: GRAPPERHAUS, Craig, A.
BUCHANAN, Robert, M.
VISHNOSKY, Nicholas, S.
YOUNG, Jason, O. E.
BATES, Paula, J.
ANDRES, Sarah, A.
CALVARY, Caleb, Aaron
Title: THIOSEMICARBAZONE DERIVATIVES AS ANTI-CANCER AGENTS
Abstract:
Some embodiments of the invention include inventive compounds (e.g., compounds of Formula (I) or (la)). Other embodiments include compositions (e.g., pharmaceutical compositions) comprising the inventive compound. Still other embodiments of the invention include compositions (e.g., pharmaceutical compositions) for treating, for example, certain diseases using the inventive compounds. Some embodiments include methods of using the inventive compound (e.g., in compositions or in pharmaceutical compositions) for administering and treating (e.g., diseases such as cancer). Further embodiments include methods for making the inventive compounds. Additional embodiments of the invention are also discussed herein.