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1. (WO2018204528) IMMUNOTHERAPEUTIC TUMOR TREATMENT METHOD
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Pub. No.: WO/2018/204528 International Application No.: PCT/US2018/030714
Publication Date: 08.11.2018 International Filing Date: 02.05.2018
IPC:
A61K 39/395 (2006.01) ,C07K 16/28 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
Applicants:
NEKTAR THERAPEUTICS [US/US]; 455 Mission Bay Boulevard South Suite 100 San Francisco, CA 94158, US
Inventors:
KIVIMAE, Saul; US
HENNESSY, Marlene; US
ANAND, Neel, K.; US
CAI, Haiying; US
DENG, Bo-Liang; US
REN, Zhongxu; US
JOSHI, Bhalchandra, V.; US
Agent:
MAHONEY, Jacqueline, F.; US
EVANS, Susan, T.; US
Priority Data:
62/500,48602.05.2017US
62/502,05105.05.2017US
Title (EN) IMMUNOTHERAPEUTIC TUMOR TREATMENT METHOD
(FR) MÉTHODE DE TRAITEMENT DE TUMEUR IMMUNOTHÉRAPEUTIQUE
Abstract:
(EN) Provided is a method of administering to a patient having cancer: (a) a 4-1BB agonist; (b) an IL-2Rβ-activating amount of a long-acting, IL-2Rβ-selective agonist; and/or (c) a toll-like receptor agonist, as well as related compositions, kits and compositions.
(FR) L'invention concerne une méthode d'administration à un patient atteint d'un cancer : (a) d’un agoniste 4-1BB; (b) d’une quantité d'activation de l'IL-2Rβ d'un agoniste sélectif de l'IL-2Rβ à action prolongée; et/ou (c) d'un agoniste de récepteur de type Toll, ainsi que des compositions, des kits et des compositions associés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)